Peptide stability is a critical factor in research reproducibility. Improper storage can lead to degradation, aggregation, and loss of biological activity. This guide covers essential protocols for handling research-grade peptides.
Store at -20°C in a desiccated environment. Most lyophilized peptides remain stable for 24+ months when stored properly. Avoid repeated freeze-thaw cycles.
Once reconstituted, peptides should be aliquoted into single-use volumes and stored at -20°C. Working solutions at 2-8°C are typically stable for 7-14 days depending on the peptide.
Custom peptide synthesis allows researchers to obtain peptides with specific sequences, modifications, and purities tailored to their experimental needs. The solid-phase peptide synthesis (SPPS) process is the industry standard.
1) Sequence submission and feasibility review, 2) Synthesis via Fmoc or Boc SPPS, 3) Cleavage and crude purification, 4) HPLC purification to target purity, 5) Analytical QC (HPLC, MS, amino acid analysis), 6) Lyophilization and packaging, 7) COA generation and cold-chain shipping.
